In this year’s Special Edition of the UN Global Compact-Accenture Strategy CEO Study, the world’s largest program of CEO research on sustainability, we focus our attention on transforming partnerships for the Sustainable Development Goals (SDGs). Following a decade of research into the views of business leaders worldwide, we examine the views of UN leaders. As the UN Secretary-General calls for enhanced cooperation between the United Nations and the private sector, we ask agency heads and partnership practitioners across the UN system: what will it take to scale up partnerships to bring about transformational impact on the SDGs?