Corporations increasingly are embracing the dual challenges of maximizing profits while also promoting the protection of human rights. The latter is at the core of corporate social responsibility and it holds the promise of being good for business. Corporate strategic philanthropy plays a central role in this dual mission of profitability and responsibility. This Good Practice Note provides the context for and offers recommendations relating to each of these elements while demonstrating how corporations are using the shift from traditional philanthropy to strategic philanthropy in the most valuable and measurable way.